Opportunities

Graduate Student (M.Sc. & Ph.D.), Post-Doctoral Research Fellow, and Clinical Fellow candidates

Do you want to make a difference to children? If being part of a multi-disciplinary team that pursues excellence in research, bridges clinical practice and leads educational endeavours through innovative strategies sounds appealing to you, this is the place you want to be.

Under the leadership of Dr. Bruce Carleton, the Division of Translational Therapeutics, Department of Pediatrics at the University of British Columbia, based at the Child & Family Research Institute (CFRI) in Vancouver, BC is seeking trainees in the areas of pharmacogenomics drug safety, drug effectiveness and drug policy. 

We are committed to studying and evaluating drug therapies with the goal of improving human health and quality of life through pharmacogenomics-focused research of adverse drug reactions.

Candidates will lead research projects that use state of the art genotyping and sequencing platforms to identify the genetic determinants of severe adverse drug reactions (ADRs) in paediatric and adult populations. In close collaboration with the CPNDS active surveillance network, genetic association and validation studies will be performed to define ADR causal genes and to develop diagnostic tests to offer personalized therapeutic recommendations for commonly used drugs. Current pharmacogenomics and surveillance focuses are: cisplatin, anthracyclines, vincristine, warfarin, codeine, inhaled corticosteroids, 5-HT₃ antagonists (antiemetics), and drugs used in the treatment of Hepatitis C. Other projects include the development of clinical practice guidelines for six drugs, and knowledge translation to implement pharmacogenomic testing in clinical practice. 

As one of the leading research centers in Canada, trainees will be exposed to both the innovative research at the Child & Family Research Institute (CFRI) and the strong academic environment of the University of British Columbia. In these stimulating and complementary surroundings, trainees will have many opportunities for advancement and interdisciplinary professional development.

Applicants with a background in pharmacogenomics, clinical pharmacology, medical genetics, experimental medicine, pediatrics, pharmacy, ethics or any other related fields are encouraged to apply. If interested, please submit a cover letter detailing research interests, curriculum vitae, writing sample and three references to: 

Gabriella Groeneweg, MA
Administration and Strategic Communications, Manager
E-mail: ggroeneweg@popi.ubc.ca